Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/9096
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Type: Journal article
Title: Intraluminal micromanometry: an evaluation of the dynamic performance of micro-extrusions and sleeve sensors
Author: Omari, T.
Bakewell, M.
Fraser, R.
Malbert, C.
Davidson, G.
Dent, J.
Citation: Neurogastroenterology and Motility, 1996; 8(3):241-245
Publisher: BLACKWELL SCIENCE LTD
Issue Date: 1996
ISSN: 1350-1925
1365-2982
Statement of
Responsibility: 
Omari, T. ; Bakewell, M. ; Fraser, R. ; Malbert, C. ; Davidson, G. ; Dent, J.
Abstract: Conventional manometric techniques are unsuitable for studies in premature infants and small laboratory animals. We have therefore developed silicone rubber 5-lumen and 10-lumen micromanometric extrusions with an o.d. 2.0 mm and lumina of 0.35 mm i.d. This study evaluates the suitability of microextrusions for intraluminal perfusion manometry. Pressure offset, post-occlusion pressure rise rate and sphincter model studies were used to assess the manometric performance of the extrusions and a miniature sleeve sensor (25 mm long) at infusion rates of 0.01-0.1 mL min-1. Micro-extrusions (5-lumen/10-lumen, respectively) had offsets (per 100 cm of length) of 3.8/5.0 mmHg at 0.01 mL min-1 and 25.6/26.2 mmHg at 0.1 mL min-1 and rise rates (in 160 cm lengths) of 64/43 mmHg sec-1 at 0.01 mL min-1 and 330/224 mmHg sec-1 at 0.1 mL min-1. Infusion rates 0.025 mL min-1 produced rise rates 100 mmHg sec-1. The miniature sleeve sensor had minimal resistance to perfusion, rise rates of 3 mmHg sec-1 at 0.01 mL min-1 and 23 mmHg sec-1 at 0.1 mL min-1 and recorded pressure as accurately as a side hole. We conclude that the performance of micromanometric extrusions and sleeves is sufficient for intraluminal perfusion manometry.
Keywords: Micromanometry; Microextrusion; Sleeve Sensor; Rise Rate; Fidelity
Rights: ©1996 Blackwell Science Ltd
RMID: 0030004789
DOI: 10.1111/j.1365-2982.1996.tb00263.x
Appears in Collections:Medicine publications

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