Adelaide Research & Scholarship
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https://hdl.handle.net/2440/9172
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| Type: | Journal article |
| Title: | ICE-like proteases in apoptosis |
| Author: | Kumar, S. |
| Citation: | Trends in Biochemical Sciences, 1995; 20(5):198-202 |
| Publisher: | Elsevier |
| Issue Date: | 1995 |
| ISSN: | 0968-0004 |
| Abstract: | The discovery of structural and functional similarities between the product of the nematode cell-death gene ced-3 and mammalian interleukin-1 beta-converting enzyme (ICE) is providing important insights into the molecular mechanism of apoptosis. This article summarizes the current knowledge of ICE and its homologues, and how these may be involved in regulating apoptosis. |
| Keywords: | Animals Humans Caenorhabditis elegans Cysteine Endopeptidases Caspase 1 Apoptosis Amino Acid Sequence Sequence Homology, Amino Acid Structure-Activity Relationship Molecular Sequence Data |
| DOI: | 10.1016/S0968-0004(00)89007-6 |
| Published version: | http://dx.doi.org/10.1016/s0968-0004(00)89007-6 |
| Appears in Collections: | Aurora harvest 4 Medicine publications |
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