Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/9247
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Beckoff, K. | - |
dc.contributor.author | MacIntosh, C. | - |
dc.contributor.author | Chapman, I. | - |
dc.contributor.author | Wishart, J. | - |
dc.contributor.author | Morris, H. | - |
dc.contributor.author | Horowitz, M. | - |
dc.contributor.author | Jones, K. | - |
dc.date.issued | 2001 | - |
dc.identifier.citation | American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 2001; 280(2):R570-R576 | - |
dc.identifier.issn | 0363-6119 | - |
dc.identifier.issn | 1522-1490 | - |
dc.identifier.uri | http://hdl.handle.net/2440/9247 | - |
dc.description | Published abstract used with permission of the copyright owner. | - |
dc.description.abstract | The aims of this study were to evaluate the effects of dietary glucose supplementation on gastric emptying (GE) of both glucose and fat, postprandial blood glucose homeostasis, and appetite in eight older subjects (4 males, 4 females, aged 65–84 yr). GE of a drink (15 ml olive oil and 33 g glucose dissolved in 185 ml water), blood glucose, insulin, gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), and appetite (diet diaries, visual analog scales, and food intake at a buffet meal consumed after the GE study) were evaluated twice, after 10 days on a standard or a glucose-supplemented diet (70 g glucose 3 times a day). Glucose supplementation accelerated GE of glucose (P , 0.05), but not oil; there was a trend for an increase in GIP (at 15 min, P 5 0.06), no change in GLP-1, an earlier insulin peak (P , 0.01), and a subsequent reduction in blood glucose (at 75 min, P , 0.01). Glucose supplementation had no effect on food intake during each diet so that energy intake was greater (P , 0.001) during the glucose-supplemented diet. Appetite ratings and energy intake at the buffet meal were not different. We conclude that, in older subjects, glucose supplementation 1) accelerates GE of glucose, but not fat; 2) modifies postprandial blood glucose homeostasis; and 3) increases energy intake. | - |
dc.description.statementofresponsibility | Katherine Beckoff, Caroline G. MacIntosh, Ian M. Chapman, Judith M. Wishart, Howard A. Morris, Michael Horowitz, and Karen L. Jones | - |
dc.language.iso | en | - |
dc.publisher | Amer Physiological Soc | - |
dc.rights | Copyright © 2001 American Physiological Society | - |
dc.source.uri | http://ajpregu.physiology.org/cgi/content/abstract/280/2/R570 | - |
dc.subject | anorexia of aging | - |
dc.subject | insulin | - |
dc.subject | gastric inhibitory polypeptide | - |
dc.subject | glucagon-like peptide-1 | - |
dc.subject | satiety | - |
dc.title | Effects of glucose supplementation on gastric emptying, blood glucose homeostasis, and appetite in the elderly | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1152/ajpregu.2001.280.2.r570 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Morris, H. [0000-0002-2745-3750] | - |
dc.identifier.orcid | Horowitz, M. [0000-0002-0942-0306] | - |
dc.identifier.orcid | Jones, K. [0000-0002-1155-5816] | - |
Appears in Collections: | Aurora harvest 4 Medicine publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.