Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/9288
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Type: Journal article
Title: Endocrinology of anorexia of ageing
Author: Chapman, I.
Citation: Best Practice & Research Clinical Endocrinology & Metabolism, 2004; 18(3):437-452
Publisher: Bailliere Tindall
Issue Date: 2004
ISSN: 1521-690X
1878-1594
Statement of
Responsibility: 
Ian McPhee Chapman
Abstract: Appetite and food intake decrease with normal ageing, predisposing to the development of under-nutrition. Under-nutrition is common in older people and has been implicated in the development and progression of chronic diseases commonly affecting the elderly, as well as in increasing mortality. An understanding of the factors that contribute to the physiological and pathological declines in food intake in older people is likely to aid in the development of effective forms of prevention and treatment. Ageing affects many of the endocrine factors involved in the control of appetite and feeding but few studies have been performed in humans to clarify these changes. Possible hormonal causes of the anorexia of ageing include increased activity of cholecystokinin, leptin and various cytokines and reduced activity of ghrelin and testosterone.
Keywords: sarcopaenia; cholecystokinin; anorexia; ghrelin; leptin; cytokines; testosterone; ageing
Rights: © 2004 Bailliere Tindall
RMID: 0020040880
DOI: 10.1016/j.beem.2004.02.004
Appears in Collections:Medicine publications

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