Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/9372
Citations
Scopus Web of Science® Altmetric
?
?
Type: Journal article
Title: Successful salvage of RAEB/AML relapsing early post allograft with FLAG-Ida conditioned mini-allograft: a report of two cases
Author: Hui, C.
Bardy, P.
Hughes, T.
Horvath, N.
To, L.
Citation: International Journal of Laboratory Hematology (Print Edition), 2001; 23(2):135-138
Publisher: Blackwell Publishing Ltd
Issue Date: 2001
ISSN: 1751-5521
0141-9854
Statement of
Responsibility: 
C.H. Hui, P. Bardy, T. Hughes, N. Horvath, L.B. To
Abstract: Management options are often limited for patients with AML or high grade myelodysplasia (MDS) relapsing within a year of allogeneic transplantation. We report, in two such patients, the use of re-induction with FLAG-Ida chemotherapy, followed by the infusion of GCSF-mobilized blood stem cells from the same HLA-matched donor. Both patients achieved durable complete remissions with good quality of life and longer disease-free survival than after the first myeloablative allografts. This mini-allograft approach offers a practical, well-tolerated salvage and a potentially curative treatment for relapsed AML/high grade MDS patients failing a first conventional myeloablative allogeneic transplants.
Keywords: Humans; Anemia, Refractory, with Excess of Blasts; Recurrence; Idarubicin; Filgrastim; Granulocyte Colony-Stimulating Factor; Recombinant Proteins; Cytarabine; Vidarabine; Antineoplastic Combined Chemotherapy Protocols; Salvage Therapy; Hematopoietic Stem Cell Transplantation; Transplantation, Homologous; Middle Aged; Female; Leukemia, Myeloid, Acute
Description: The definitive version may be found at www.wiley.com
Provenance: Published Online: 20 Dec 2001
Rights: Copyright © 2001 Blackwell Science Limited
RMID: 0020011060
DOI: 10.1046/j.1365-2257.2001.00359.x
Appears in Collections:Medicine publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.