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|Scopus||Web of Science®||Altmetric|
|Title:||Crosstalk between mTOR complexes|
|Citation:||Nature Cell Biology, 2013; 15(11):1263-1265|
|Publisher:||Nature Publishing Group|
|Jianling Xie and Christopher G. Proud|
|Abstract:||The mTOR protein kinase controls anabolic processes as part of mTOR complexes 1 and 2 (mTORC1 and mTORC2). The two complexes are now shown to be involved in a negative feedback regulatory mechanism, in which mTORC1 stimulation inactivates mTORC2 through the inhibitory phosphorylation of the mTORC2 component Sin1.|
|Rights:||© 2013 Macmillan Publishers Limited. All rights reserved.|
|Appears in Collections:||Molecular and Biomedical Science publications|
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