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https://hdl.handle.net/2440/28004
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Type: | Journal article |
Title: | ARID proteins come in from the desert |
Author: | Kortschak, R. Tucker, P. Saint, R. |
Citation: | Trends in Biochemical Sciences, 2000; 25(6):294-299 |
Publisher: | Elsevier Science London |
Issue Date: | 2000 |
ISSN: | 0968-0004 1362-4326 |
Organisation: | Centre for the Molecular Genetics of Development |
Statement of Responsibility: | R. Daniel Kortschak, Philip W. Tucker and Robert Saint |
Abstract: | Members of the recently discovered ARID (AT-rich interaction domain) family of DNA-binding proteins are found in fungi and invertebrate and vertebrate metazoans. ARID-encoding genes are involved in a variety of biological processes including embryonic development, cell lineage gene regulation and cell cycle control. Although the specific roles of this domain and of ARID-containing proteins in transcriptional regulation are yet to be elucidated, they include both positive and negative transcriptional regulation and a likely involvement in the modification of chromatin structure. |
Keywords: | DNA-binding protein Transcription factor Chromatin Development Evolution |
Description: | Copyright © 2000 Elsevier Science Ltd. All rights reserved. |
DOI: | 10.1016/S0968-0004(00)01597-8 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/405916/description#description |
Published version: | http://dx.doi.org/10.1016/s0968-0004(00)01597-8 |
Appears in Collections: | Aurora harvest 6 Centre for the Molecular Genetics of Development publications Molecular and Biomedical Science publications |
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