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https://hdl.handle.net/2440/46942
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Type: | Journal article |
Title: | Hypertension: Its prevalence and population-attributable fraction for mortality from cardiovascular disease in the Asia-Pacific region |
Author: | Martiniuk, A. Lee, C. Lawes, C. Ueshima, H. Suh, I. Lam, T. Gu, D. Feigin, V. Jamrozik, K. Ohkubo, T. Woodward, M. |
Citation: | Journal of Hypertension, 2007; 25(1):73-79 |
Publisher: | Lippincott Williams & Wilkins |
Issue Date: | 2007 |
ISSN: | 0263-6352 |
Statement of Responsibility: | Martiniuk AL, Lee CM, Lawes CM, Ueshima H, Suh I, Lam TH, Gu D, Feigin V, Jamrozik K, Ohkubo T, Woodward M and Asia-Pacific Cohort Studies Collaboration |
Abstract: | OBJECTIVE: About half of the world's burden of cardiovascular disease is carried by countries in the Asia-Pacific region. This study aimed to quantify the contribution of hypertension to cardiovascular diseases (CVD) at the country level, by calculating the sex-specific, population-attributable fractions (PAFs) for fatal ischaemic heart disease (IHD) and stroke (haemorrhagic and ischaemic) for the World Health Organization Western Pacific and South-east Asian regions. METHODS: The most recent sex-specific prevalence data on hypertension were sought. Age-adjusted hazard ratio (HR) estimates for fatal IHD and stroke associated with hypertension were obtained using Cox analyses of individual participant cohort data from 600,000 adult participants in the Asia-Pacific Cohort Studies Collaboration. HR estimates and prevalence were then used to calculate sex-specific PAFs for fatal IHD and stroke, by country. RESULTS: In 15 countries with available data, the prevalence of hypertension ranged from 5-47% in men and from 7-38% in women. Overall, the fraction of IHD attributable to hypertension ranged from 4-28% in men and from 8-39% in women. Corresponding ranges for haemorrhagic stroke were 18-66% and 15-49%, and for ischaemic stroke were 8-44% and 12-45%. CONCLUSIONS: In the Asia-Pacific region, up to 66% of some subtypes of CVD can be attributed to hypertension, underscoring the immense impact that blood pressure- lowering strategies could have in this populous region. |
Description: | Copyright © 2007, Lippincott Williams & Wilkins |
DOI: | 10.1097/HJH.0b013e328010775f |
Published version: | http://www.jhypertension.com/pt/re/jhypertension/abstract.00004872-200701000-00012.htm |
Appears in Collections: | Aurora harvest Public Health publications |
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