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https://hdl.handle.net/2440/57620
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Type: | Journal article |
Title: | Resistance of degraded hair shafts to contaminant DNA |
Author: | Gilbert, M. Menez, L. Janaway, R. Tobin, D. Cooper, A. Wilson, A. |
Citation: | Forensic Science International, 2006; 156(2):208-212 |
Publisher: | Elsevier Sci Ireland Ltd |
Issue Date: | 2006 |
ISSN: | 0379-0738 1872-6283 |
Statement of Responsibility: | M Thomas P Gilbert, Laura Menez, Robert C Janaway, Desmond J Tobin, Alan Cooper and Andrew S Wilson |
Abstract: | We have investigated the susceptibility of degraded human hair shaft samples to contamination by exogenous sources of DNA, including blood, saliva, skin cells, and purified DNA. The results indicate that on the whole hair shafts are either largely resistant to penetration by contaminant DNA, or extremely easy to successfully decontaminate. This pertains to samples that are both morphologically and biochemically degraded. We suggest that this resistance to the incorporation of contaminant DNA relates to the hydrophobic and impermeable nature of the keratin structures forming the hair shaft. Therefore, hair samples represent an important and underestimated source of DNA in both forensic and ancient DNA studies. |
Keywords: | Contamination Degradation Hair mtDNA |
DOI: | 10.1016/j.forsciint.2005.02.021 |
Description (link): | http://www.fsijournal.org/home |
Published version: | http://dx.doi.org/10.1016/j.forsciint.2005.02.021 |
Appears in Collections: | Aurora harvest Earth and Environmental Sciences publications Environment Institute Leaders publications |
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