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Results 11-17 of 17 (Search time: 0.003 seconds).
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Issue Date
Title
Author(s)
2007
Imatinib increases the intracellular concentration of nilotinib which may explain the observed synergy between these drugs
White, D.
;
Saunders, V.
;
Quinn, S.
;
Manley, P.
;
Hughes, T.
2010
Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with Imatinib
White, D.
;
Dang, P.
;
Engler, J.
;
Frede, A.
;
Osborn, M.
;
Saunders, V.
;
Manley, P.
;
Zrim, S.
;
Hughes, T.
2008
Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications
Hiwase, D.
;
Saunders, V.
;
Hewett, D.
;
Frede, A.
;
Zrim, S.
;
Dang, P.
;
Eadie, L.
;
To, L.
;
Vaz de Melo, J.
;
Kumar, S.
;
Hughes, T.
;
White, D.
2013
Dasatinib targets chronic myeloid leukemia-CD34⁺ progenitors as effectively as it targets mature cells
Hiwase, D.
;
Saunders, V.
;
Nievergall, E.
;
Ross, D.
;
White, D.
;
Hughes, T.
2012
Chronic phase chronic myeloid leukemia patients with low OCT-1 activity randomized to high-dose imatinib achieve better responses and have lower failure rates than those randomized to standard-dose imatinib
White, D.
;
Radich, J.
;
Soverini, S.
;
Saunders, V.
;
Frede, A.
;
Dang, P.
;
Cilloni, D.
;
Lin, P.
;
Mongay, L.
;
Woodman, R.
;
Manley, P.
;
Slader, C.
;
Kim, D.
;
Pane, F.
;
Martinelli, G.
;
Saglio, G.
;
Hughes, T.
2013
Degree of kinase inhibition achieved in vitro by imatinib and nilotinib is decreased by high levels of ABCB1 but not ABCG2
Eadie, L.
;
Saunders, V.
;
Hughes, T.
;
White, D.
2017
Increased peroxisome proliferator-activated receptor γ activity reduces imatinib uptake and efficacy in chronic myeloid leukemia mononuclear cells
Wang, J.
;
Lu, L.
;
Kok, C.
;
Saunders, V.
;
Goyne, J.
;
Dang, P.
;
Leclercq, T.
;
Hughes, T.
;
White, D.
Discover
Author
16
White, D.
7
Dang, P.
7
Frede, A.
5
Engler, J.
5
Hiwase, D.
5
Manley, P.
5
Zrim, S.
4
Zannettino, A.
3
Eadie, L.
3
Kok, C.
.
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Subject
11
Humans
9
Leukemia, Myelogenous, Chronic, B...
9
Pyrimidines
8
Imatinib Mesylate
7
Antineoplastic Agents
7
Benzamides
7
Piperazines
5
Organic Cation Transporter 1
4
CML
4
Fusion Proteins, bcr-abl
.
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Date issued
1
2020 - 2022
12
2010 - 2019
4
2006 - 2009