Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/61218
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Type: Journal article
Title: Adult height and cancer mortality in Asia: the Asia Pacific Cohort Studies Collaboration
Author: Batty, David G.
Barzi, Federica
Woodward, Mark
Jamrozik, Konrad
Woo, Jean
Kim, Hyeon Chang
Ueshima, Hirotsugu
Huxley, Rachel R.
Citation: Annals of Oncology, 2010; 21(3):646-654
Publisher: Oxford University Press
Issue Date: 2010
ISSN: 0923-7534
School/Discipline: School of Population Health and Clinical Practice : Public Health
Statement of
Responsibility: 
G. D. Batty, F. Barzi, M. Woodward, K. Jamrozik, J. Woo, H. C. Kim, H. Ueshima, R. R. Huxley and for the Asia Pacific Cohort Studies Collaboration
Abstract: Background: The observation that taller people experience an increased risk of selected cancers is largely restricted to Caucasian cohorts. These associations may plausibly differ in Asian populations. For the first time, we make direct comparison in the same analyses of the associations between height and a series of malignancies in Australasian (Caucasian) and Asian populations. Methods: Analyses were based on the Asia Pacific Cohort Studies Collaboration of 506 648 study participants (408 381 Asia, 98 267 Australasia) drawn from 38 population-based cohort studies. Cox proportional hazards regression was used to estimate the relationship between height and cancer rates. Results: A total of 3 272 600 person-years of follow-up gave rise to 7497 cancer deaths (4415 in Asia; 3082 in Australasia). After multiple adjustments and left censoring, taller individuals experienced increased rates of carcinoma of the intestine (men and women); all cancers, liver, lung, breast, ‘other’ malignancies (all women); and cancers of the prostate and bladder (men). No consistent regional (Asia versus Australasia) or sex differences were observed. Conclusions: In the present study, taller men and women had an elevated risk of selected malignancies. These associations did not differ appreciably between Asian and Caucasian populations.
Keywords: Asia; body height; cancer; malignancy; stature
Rights: © The Author 2010. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved
RMID: 0020095946
DOI: 10.1093/annonc/mdp363
Appears in Collections:Public Health publications

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