Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/75
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Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Macdonald, J. | - |
dc.contributor.author | Hrmova, M. | - |
dc.contributor.author | Fincher, G. | - |
dc.contributor.author | Stick, R. | - |
dc.date.issued | 2004 | - |
dc.identifier.citation | Australian Journal of Chemistry: an international journal for chemical science, 2004; 57(3):187-191 | - |
dc.identifier.issn | 0004-9425 | - |
dc.identifier.issn | 1445-0038 | - |
dc.identifier.uri | http://hdl.handle.net/2440/75 | - |
dc.description.abstract | The glycosylation of 4,6-O-benzylidene-N-benzyloxycarbonylisofagomine with a D-glucosyl and a laminari-biosyl trichloroacetimidate has given, after removal of protecting groups, 3-O-(β-D-glucopyranosyl)- and 3-O-(β-laminaribiosyl)-isofagomines. Also included are similar glycosylations of a related tetrahydrooxazine. 3-O-(β-D-Glucopyranosyl)- and 3-O-(β-laminaribiosyl)-isofagomines acted as potent inhibitors of a barley 1,3-β-D-glucan endo-hydrolase, with ID₅₀ values of 7.8 and 3.1 μM, respectively. | - |
dc.description.statementofresponsibility | James M. Macdonald, Maria Hrmova, Geoffrey B. Fincher and Robert V. Stick | - |
dc.language.iso | en | - |
dc.publisher | C S I R O Publishing | - |
dc.source.uri | http://dx.doi.org/10.1071/ch03227 | - |
dc.subject | Glycosides | - |
dc.subject | synthesis (org.) | - |
dc.subject | enzyme inhibitors | - |
dc.subject | glycosylation | - |
dc.subject | endo-hydrolases | - |
dc.title | The synthesis of 3-O-(beta-D-glucopyranosyl)- and 3-O-(beta-laminaribiosyl)-isofagomines, potent inhibitors of a 1,3-beta-D-glucan endo-hydrolase | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1071/CH03227 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Hrmova, M. [0000-0002-3545-0605] | - |
Appears in Collections: | Agriculture, Food and Wine publications Aurora harvest 6 |
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