Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/76533
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Type: Journal article
Title: Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera
Author: Baxter, S.
Badenes-Perez, F.
Morrison, A.
Vogel, H.
Crickmore, N.
Kain, W.
Wang, P.
Heckel, D.
Jiggins, C.
Citation: Genetics, 2011; 189(2):675-679
Publisher: Genetics
Issue Date: 2011
ISSN: 0016-6731
1943-2631
Statement of
Responsibility: 
Simon W. Baxter, Francisco R. Badenes-Pérez, Anna Morrison, Heiko Vogel, Neil Crickmore, Wendy Kain, Ping Wang, David G. Heckel, and Chris D. Jiggins
Abstract: Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.
Keywords: Animals; Lepidoptera; Moths; Bombyx; Bacterial Proteins; Multidrug Resistance-Associated Proteins; Insect Proteins; Endotoxins; Chromosome Mapping; Sequence Analysis, DNA; Evolution, Molecular; Phylogeny; Species Specificity; Synteny; Insecticide Resistance; Mutation; Molecular Sequence Data; Female; Male; Hemolysin Proteins; Genetic Variation; Chromosomes, Insect
Rights: Copyright © 2011 by the Genetics Society of America
RMID: 0020123951
DOI: 10.1534/genetics.111.130971
Appears in Collections:Molecular and Biomedical Science publications
Environment Institute publications

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